“NeuroReformer®’s patented technology restores cellular function with precision unmatched by any other device in the world.”
– Dr. Gianluca D’ippolito, Ph.D., Stem Cell Biology, University Professor, Biomedical Engineering
The Only Micro-Precision Solution for Neural Recovery
NeuroReformer® is the only FDA cleared Class-II medical device that integrates various patented technologies, including NeuroFrequency Mapping™ and Adaptive NeuroFrequency Stabilization™, to deliver precise and stable neurofrequency signals, uniquely supporting axon reconnection and eliminating erratic signaling. Unlike conventional stimulation devices that rely on broad, unstable frequencies, NeuroReformer®’s ground-breaking technology replicates exact neurofrequency patterns and dynamically adapts during physical therapy movements. This unparalleled micro-precision technology is the only one of its kind on the market, enabling cellular-level changes that ensure superior neural recovery outcomes.
Next-Generation Advancements
NeuroReformer® + Movement = Faster Recovery
NeuroFrequency Replication Therapy™ combines replicated neurofrequencies with precise movement patterns to restore neuromuscular function, correct biomechanical misalignments, and accelerate recovery. [MORE]
Smart Frequency Detection
NeuroReformer® uses a patented scanning process to identify optimal neurofrequencies for each individual. Unlike traditional neurotherapy devices that deliver broad-spectrum neural stimulation, NeuroReformer® customizes treatment by scanning for precise neurological and neuromuscular frequencies, ensuring faster and more effective recovery. [MORE]
Adaptive NeuroFrequency Stabilization™ is a patented real-time frequency regulation system designed to maintain the precision and effectiveness of neurofrequency treatment during movement-based rehabilitation. Unlike conventional neurotherapy devices, which experience signal disruptions and inconsistencies during active therapy, NeuroReformer® dynamically adjusts and stabilizes neurofrequencies in real time, ensuring continuous therapeutic efficacy.
[MORE]The Science Behind the Breakthrough
Revolutionizing Precision Healing at the Cellular Level
NeuroReformer® integrates AI-calibrated computing with targeted neurofrequency signals to restore atrophied nerve and muscle cells, enhance synaptic transmission, and promote axonal repair. Unlike earlier-generation devices that rely on fixed frequency presets, NeuroReformer® dynamically scans and customizes treatment in real-time, tailoring precise frequencies to each patient. The result: deeper neural restoration and significantly accelerated recovery. [MORE]
The NeuroReformer®'s Axonal Effect
Axons transmit electrical impulses that regulate movement, sensation, and coordination. These impulses, known as action potentials, form rhythmic neurofrequencies essential for nervous system function. Injury, atrophy, or degeneration can disrupt these signals, leading to erratic transmission and impaired function. NeuroReformer® precisely measures neurofrequencies in affected areas and delivers optimized, replicated signals to restore axonal function, enhance neural communication, and accelerate nerve and muscle recovery. [MORE]
Restoring Synaptic Function for Faster Recovery
Synapses transmit signal between neurons and muscles, regulating movement, pain perception, and healing. Injury, inflammation, or neural fatigue can disrupt this process, leading to pain and delayed recovery. NeuroReformer® restores communication by applying targeted neurofrequencies, enhancing cellular energy, reducing inflammation, and optimizing conditions for regeneration. [MORE]
NeuroReformer®: Advanced Pain Relief Through Neural Repair
NeuroReformer® alleviates pain by restoring disrupted neural connections, reducing inflammation, and rebalancing muscle coordination. It detects neurological disconnects, retrains atrophied nerves, and eliminates guarding postures that prolong discomfort. By enhancing synaptic communication and activating the body's natural pain-gating mechanisms, NeuroReformer® provides fast, lasting relief while accelerating recovery. [MORE]
Restoring Natural Movement & Function
NeuroReformer® retrains neuromuscular responses by disrupting compensatory patterns, restoring proper muscle activation, and optimizing coordination for lasting recovery. By replicating natural neural frequencies, it promotes homeostasis, accelerates cellular regeneration, and enhances physical therapy outcomes—ensuring stable neurofrequency support during movement for maximum rehabilitation efficiency. [MORE]
NeuroReformer®: Accelerating Recovery at the Cellular Level
NeuroReformer® enhances the body's natural healing process by restoring neural communication, improving circulation, and reducing inflammation. Its AI-calibrated neurofrequencies optimize cellular repair, promote axonal and synaptic regeneration, and ensure stable treatment effectiveness even during movement-based therapy—leading to faster, more complete recovery. [MORE]
NeuroReformer® vs. Other Modalities
More About NeuroFrequency Replication Therapy™
NeuroFrequency Replication Therapy™ (NFRT™) is a patented treatment approach that pairs dual-channel neurofrequency stimulation with targeted physical movements to rapidly restore neuromuscular function. It addresses the root cause of dysfunction by simultaneously reactivating dormant nerve and muscle tissue while correcting movement imbalances in real time.
At the start of each session, the NeuroReformer® device scans the patient’s body and identifies their optimal NeuroLogical and NeuroMuscular frequencies. These personalized waveforms are then replicated and applied during therapeutic movements, allowing the nervous system to reorganize more efficiently.
When paired with movement, these tailored frequencies help:
- Retrain the brain and body to fire correctly, improving motor recruitment and coordination
- Restore biomechanical alignment, reducing compensatory strain and faulty movement patterns.
- Accelerate cellular repair by enhancing circulation and decreasing
Unlike modalities that simply suppress symptoms, NFRT™ reprograms the body’s own neuro-signaling for long-term healing and measurable performance improvement.
More About How the NeuroReformer® Works
NeuroReformer®’s proprietary system begins by conducting a real-time impedance analysis to establish baseline neural conductivity. From there, it initiates NeuroFrequency Mapping™—a patented process that identifies each patient’s unique NeuroLogical and NeuroMuscular frequencies. These two signal sets are then independently replicated and combined into a synchronized dual-frequency waveform.
This waveform is delivered directly to he dysfunctional region, re-establishing disrupted neural communication and activating dormant or misfiring motor pathways. At the cellular level, this promotes mitochondrial activity, upregulates neurotrophic factors, and reduces inflammation—creating the ideal conditions for neuroplasticity and tissue regeneration.
Because the system is fully adaptive, it self-adjusts frequency output based on continuous real0time biofeedback, maintaining optimal engagement with the patient’s evolving physiological state. This closed-loop process makes NeuroReformer® ideal for complex injuries, chronic neurological conditions, and performance rehabilitation—without the guesswork of conventional e-stim protocols.
More About Axonal Repair
By re-establishing proper neurofrequency patterns, the NeuroReformer® reduces signal disruption, improves synaptic transmission, and promotes axonal regeneration. Together, these effects enhance neuromuscular coordination, alleviate pain, and restore mobility, delivering precise therapeutic results that revitalize nervous system function and support recovery.
- Combating the Root Causes of Axonal Repair: NeuroReformer® combats the primary barriers to axonal repair, such as inflammation, oxidative stress, and poor circulation. By applying tailored neurofrequencies, it replicates healthy neuron activity to stimulate axonal regrowth and enhance Schwann cell function, which releases neurotrophic factors that guide regrowth and restore damaged neural pathways.
- Activating Neurotrophic Factors: Tailored neurofrequencies from NeuroReformer® stimulate the release of critical growth factors, including Brain-Derived Neurotrophic Factor (BDNF) and Nerve Growth Factor (NGF). These factors support neuron survival, encourage axonal sprouting, and promote remyelination by regenerating protective myelin sheaths.
- Supporting Remyelination: Through targeted stimulation of oligodendrocytes (cells responsible for myelin production), NeuroReformer® promotes remyelination, restoring the insulating sheaths needed for efficient nerve signal conduction and overall neural health.
- Reducing Inflammation and Oxidative Stress: NeuroReformer® creates an optimal healing environment by lowering levels of inflammatory cytokines and reactive oxygen species. This reduction minimizes tissue damage and enhances the conditions necessary for axonal repair.
Improving Circulation and Oxygen Delivery: By increasing microcirculation, NeuroReformer® ensures that repair sites receive adequate oxygen and essential nutrients. It also facilitates the removal of cellular debris and waste products that could otherwise hinder the recovery process.
NeuroReformer®’s Role in Pain Alleviation
- Identifying Neurological Disconnects: Pain often originates from disruptions in neural connection. NeuroReformer® precisely detects these disconnects and delivers tailored neurofrequencies to restore proper signaling, reducing pain and retraining atrophied nerves and muscles.
- Eliminates Guarding Postures: Injury-induced guarding postures and proprioceptive imbalances can prolong pain. NeuroReformer® targets these disruptions with precision neurofrequencies, alleviating barriers, reducing discomfort, and accelerating recovery beyond natural rates.
Pain Reduction Mechanisms
- Restoring Neural Communication: NeuroReformer® recalibrates dysfunctional pathways by enhancing synaptic communication and replicating natural neurofrequencies, preventing pain signal over-amplification and significantly reducing perceived pain.
- Reducing Inflammation and Oxidative Stress: Through improved circulation and anti-inflammatory molecule release, NeuroReformer® reduces chronic inflammation and oxidative stress, alleviating pain and fostering healing in damaged areas.
- Activating Pain-Gate Mechanisms: NeuroReformer® engages Aß sensory fibers to override pain signals from smaller fibers, effectively “closing the gate” on pain signals before they reach the brain, offering fast and sustained relief.
Restored Biomechanical Function
NeuroReformer®️ disrupts compensatory movement patterns by stimulating muscle fibers and re-educating neuromuscular responses. This process re-establishes proper muscle activation and coordination, enabling the body to regain natural movement and achieve long-term functional recovery.
Biological Rationale
- Promoting Homeostasis: NeuroReformer®️ helps restore balance disrupted by injuries or conditions like neuropathy by replicating natural neural frequencies, enabling the body to achieve homeostasis.
- Cellular Regeneration: Enhancing synaptic environments accelerates tissue repair, supports regeneration, and releases neurotrophic factors critical for recovery.
- Integration into Therapy: NeuroReformer®️ complements physical therapy techniques by maintaining stable neurofrequencies during rehab movements. This synergy aligns with the body’s natural processes, optimizing the reprogramming of atrophied muscles and nerves while effectively restoring biomechanical function.
Empowering Faster Recovery at the Cellular Level
NeuroReformer®️amplifies the body’s natural healing capacity with AI-calibrated frequencies that address neural disconnects and optimize recovery. Key benefits include:
- Restoring Cellular Communication: Aligns disrupted pathways to resolve pain and injury at the cellular level.
- Improving Circulation: Delivers oxygen, and nutrients to repair tissues faster.
- Supporting Regeneration: Encourages cellular repair while reducing inflammation for long-term healing.
How NeuroReformer® Accelerates Healing
- Neurological-Level Stimulation: Unlike traditional stimulators units, NeuroReformer® replicates patient-specific neurofrequencies to enhance tissue repair and neuromuscular function.
- Optimizing Cellular Repair: Improves nutrient delivery and waste removal to create an ideal healing environment.
- Boosting Axonal and Synaptic Functions: Promotes regeneration and plasticity, essential for recovery and therapy adaptation.
- Ensuring Stability During Movement: Patented Adaptive NeuroFrequency Stimulation™ maintains treatment effectiveness during physical therapy exercises.
More About Neural Connections
Key Mechanisms Supported by NeuroReformer®:
- Synaptic Frequency Optimization: Stabilized neurofrequencies realign disrupted pathways and restore communication across the synaptic cleft, enhancing transmission efficiency.
- Neuroplasticity Stimulation: Repetitive neurofrequencies stimulate neurotrophic factors like BDNF, aiding in injury recovery and supporting motor and cognitive tasks.
- Fatigue Reduction: Targeted frequencies replenish neurotransmitter reserves and improve ionic flow, ensuring sustained communication and reducing synaptic fatigue.
- Enhanced Circulation: Increased blood flow and oxygenation deliver essential nutrients while clearing metabolic waste, reducing inflammation and promoting repair.
- Electrophysiological Regulation: Stabilized neurofrequencies regulate neuron membrane potentials, reducing erratic signaling and improving transmission.
- Pain Modulation: Activation of Aß fibers overrides pain pathways (Gate Control Theory of Pain), alleviating discomfort and retraining neurons for proper signaling.
- Cellular Regeneration: The optimized synaptic environment accelerates cellular repair and regeneration of atrophied nerves and muscles.
More About Adaptive NeuroFrequency Stabilization™
Adaptive NeuroFrequency Stabilization™ is NeuroReformer®’s proprietary system that actively regulates treatment delivery during patient movements. Traditional neurotherapy devices often struggle to maintain consistent output once a patient begins dynamic rehab activities, leading to signal dropout, uneven stimulation, and reduced therapeutic impact.
NeuroReformer® overcomes this limitation by continuously monitoring:
- Tissue impedance
- Patient movement patterns
- Real-time intensity and current feedback
This system then auto-adjusts the waveform delivery on both channels, preserving frequency accuracy and treatment intensity throughout the full arc of motion—from isometric holds to dynamic resistance exercises. This allows clinicians to:
- Apply the therapy during functional movement, not just rest
- Maintain consistent neuromuscular re-education during activity
- Optimize motor recruitment without manual recalibration
In short, Adaptive NeuroFrequency Stabilization™ ensures that every rep, step, or stretch is treated with the same calibrated precision, helping patients build strength, improve coordination, and restore neuromuscular control without interruption.
More About NeuroFrequency Mapping™
NeuroFrequency Mapping™ is a patented diagnostic protocol built into the NeuroReformer® that identifies each patient’s optimal therapeutic frequencies in real time. Instead of applying generic stimulation, the system performs a two phase scan to detect the individual’s ideal NeuroLogical and NeuroMuscular frequencies—measured in hertz— based on their tissue conductivity, impedance, and neural response.
This dual-scan process allows NeuroReformer® to:
- Calibrate stimulation to the patient’s unique physiology
- Target specific neurological dysfunctions with precision
- Minimize over- or under-stimulation which can slow recovery or cause adaptation
Each scan is displayed visually, giving providers confidence that the treatment is aligned with the patient’s current state of injury, inflammation, or dysfunction. This mapping process is completed in under 60-seconds and automatically adapts to changes in the patient’s condition over time.
By identifying the exact frequencies where the nervous system is most responsive, NeuroFrequency Mapping™ lays the groundwork for personalized, effective therapy and ensures every treatment starts with a data-driven foundation.
Features | NeuroReformer® | Neubie |
Type of Output | Direct Current | Direct Current |
Active or Passive | Can be both | Can be both |
Evidence of impact on Muscle Hypertrophy | Yes | Yes |
FDA Cleared For: | ||
Maintaining or increasing range of motion |  | |
Increasing local blood circulation | | |
Neuromuscular Re-education | | |
Preventing atrophy | | |
Reducing Spasms | | |
Preventing venous thrombosis after surgery | | |
Management or relief of chronic pain | | |
Management of post-surgical and post-traumatic pain | |  |
Replicating Exact Frequencies | | |
Stabilizing Frequencies | | |
NeuroTropic Detection | | |
No unpleseant feeling during movement | | |
Features | NeuroReformer® | Shockwave |
Type of Output | Direct Current | Mechanical Impulses |
Active or Passive | Can be both | Passive |
Evidence of impact on Muscle Hypertrophy | Yes | None |
FDA Cleared For: | ||
Maintaining or increasing range of motion | | |
Increasing local blood circulation | | |
Neuromuscular Re-education | | |
Preventing atrophy | | |
Reducing Spasms | | |
Preventing venous thrombosis after surgery | | |
Management or relief of chronic pain | | |
Management of post-surgical and post-traumatic pain | | |
Features | NeuroReformer® | Laser |
Type of Output | Direct Current | Light Energy |
Active or Passive | Can be both | Passive |
Evidence of impact on Muscle Hypertrophy | Yes | None |
FDA Cleared For: | ||
Maintaining or increasing range of motion | | |
Increasing local blood circulation | | |
Neuromuscular Re-education | | |
Preventing atrophy | | |
Reducing Spasms | | |
Preventing venous thrombosis after surgery | | |
Management or relief of chronic pain | | |
Management of post-surgical and post-traumatic pain | | |
Features | NeuroReformer® | PEMF |
Type of Output | Direct Current | Pulsed Magnetic Fields |
Active or Passive | Can be both | Passive |
Evidence of impact on Muscle Hypertrophy | Yes | None |
FDA Cleared For: | ||
Replciating Exact Frequencies | | |
Stabilizing Frequencies | | |
NeuroTroptic Detection | | |
No Unpleasent Feeling During Movement | | |
Maintaining or increasing range of motion | | |
Increasing local blood circulation | | |
Neuromuscular Re-education | | |
Preventing atrophy | | |
Reducing Spasms | | |
Preventing venous thrombosis after surgery | | |
Management or relief of chronic pain | | |
Management of post-surgical and post-traumatic pain | | |
Features | NeuroReformer® | ARPWave |
Type of Output | Direct Current | Direct Current |
Active or Passive | Can be both | Passive |
Evidence of impact on Muscle Hypertrophy | Yes | Minimal |
FDA Cleared For: | ||
Replicating Exact NeuroFrequencies | | |
Stabilizing Frequencies | | |
NeuroTropic Detection | | |
No unpleasent feeling during movement | | |
Maintaining or increasing range of motion | | |
Increasing local blood circulation | | |
Neuromuscular Re-education | | |
Preventing atrophy | | |
Reducing Spasms | | |
Management of post-surgical and post-traumatic pain | | |
Management or relief of chronic pain | | |
Preventing venous thrombosis after surgery | | |
Features | NeuroReformer® | TENS Unit |
Type of Output | Direct Current | Alternating Current |
Active or Passive | Can be both | Passive |
Evidence of impact on Muscle Hypertrophy | Yes | Minimal |
FDA Cleared For: | ||
Replicating Exact Frequencies | | |
Stabilizing Frequencies | | |
NeuroTropic Detection | | |
No Unpleasant Feeling During Movement | | |
Maintaining or increasing range of motion | | |
Increasing local blood circulation | | |
Neuromuscular Re-education | | |
Preventing atrophy | | |
Reducing Spasms | | |
Preventing venous thrombosis after surgery | | |
Management or relief of chronic pain | | |
Management of post-surgical and post-traumatic pain | | |
